This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that ...
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Interferon regulatory factor 3 - Homo sapiens (Human) | UniProtKB
www.uniprot.org › uniprotkb › entry
Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA ...
Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. IRF3. Available structures. PDB, Ortholog search: PDBe RCSB ...
IRF3
Protein
Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. Wikipedia
Cellular component: cytoplasm; nucleoplasm; nucleus; cytosol
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that ...
7 days ago · Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; identical protein binding ...
IRF3 is a transcription factor that controls multiple IFN-inducing pathways, including the TLR3 pathway, which can be triggered by dsRNA, and the pathways ...
Apr 30, 2018 · IFN regulatory factor 3 (IRF3) is a transcription regulator of cellular responses in many cell types that is known to be essential for innate ...
Nov 6, 2017 · Interruption of IRF3-dependent signaling resulted in decreased cardiac expression of inflammatory cytokines and chemokines and decreased ...
The IRF3 gene encodes interferon regulatory factor-3, a transcription factor that activates transcription of interferon (see, e.g., IFNB1, 147640)-related ...
Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA ...
