IRF3
Protein
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Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. Wikipedia
Cellular component: cytoplasm; nucleoplasm; nucleus; cytosol
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Apr 13, 2024 · The function of IRF3 is a critical node in TLR signaling pathways, which is central for the induction of important polarizing cytokines. These ...
Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA ...
Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. IRF3. Available structures. PDB, Ortholog search: PDBe RCSB ...
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This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that ...
Apr 11, 2024 · Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; identical protein binding ...
IRF3 is a transcription factor that controls multiple IFN-inducing pathways, including the TLR3 pathway, which can be triggered by dsRNA, and the pathways ...
IRF3 (interferon response factor 3) is a 60 kDa member of the IRF family of proteins. Human IRF3 contains one DNA binding domain (aa 7‑107), a nuclear export ...
Apr 30, 2018 · IFN regulatory factor 3 (IRF3) is a transcription regulator of cellular responses in many cell types that is known to be essential for innate ...
Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA ...
Nov 6, 2017 · Interruption of IRF3-dependent signaling resulted in decreased cardiac expression of inflammatory cytokines and chemokines and decreased ...