Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. It is a member of the toll-like receptor (TLR) family.
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Apr 11, 2024 · TLR5 is expressed in Type II dendritic cells in the terminal ileum. These cells are sensitive to TNFR1/TNFR2-dependent cell death which drives ...
Nov 20, 2017 · TLR5 signaling in the liver modulates local immunity by secreting cytokines and chemo-attracting immunocytes, such as neutrophils, macrophages, ...
TLR5 may act as both an immune sensor and as a receptor to capture flagellated bacteria. Flagellin is a potent immune activator, stimulating diverse biologic ...
7 days ago · TLR5 is a new reporter for triple-negative breast cancer indicated by radioimmunoimaging and fluorescent staining. TLR5: A prognostic and ...
Jan 2, 2024 · In our study, we show that stimulating toll-like receptor 5 (TLR5) via mucosal delivery of a flagellin-containing fusion protein effectively ...
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune ...
TLR5 is an extracellular sensor activated by bacterial flagellin and activates T cells when presented by APCs74 or when directly administered to CD4+ and CD8+ T ...
Jan 24, 2024 · A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of ...
Among TLRs, TLR5 is the receptor for flagellin, the major constituent of bacterial flagella and a virulence factor for Gram-negative and Gram-positive bacteria ...