SRB5 (also called MED18) encodes a component of the head module of the Mediator transcriptional regulation complex. The Mediator complex is highly conserved ...
Mar 8, 2013 · Background: Mediator subunit Srb5/Med18 is required for termination of transcription by RNAP II. Results: Srb5/Med18 does not affect ...
SRB5 Srb5p []. Gene ID: 852996, updated on 4-Feb-2024. Summary. Enables RNA polymerase II core promoter sequence-specific DNA binding activity and ...
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.
The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae.
We provide four lines of evidence that Mediator subunit Srb5/Med18 is involved in the termination of transcription of a subset of genes in budding yeast. First, ...
Srb5/Med18-mediated Termination of Transcription Is Dependent on ...
www.jbc.org › article › fulltext
Mar 8, 2013 · Here, we show that the CTD-Ser2 phosphorylation pattern on Srb5/Med18-dependent genes remains unchanged in the absence of Srb5 in cells.
Enables RNA polymerase II core promoter sequence-specific DNA binding activity and transcription coactivator activity. Involved in positive regulation of ...
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.