Jul 12, 2012 · KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. In combination with mathematical ...
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KL001 is a first-in-class cryptochrome (CRY, a flavoproteins that are sensitive to blue light, and is involved in the circadian rhythms of plants and animals) ...
Aug 31, 2012 · From an unbiased cell-based circadian phenotypic screen, we identified KL001, a small molecule that specifically interacts with cryptochrome ( ...
KL 001 is a cryptochrome protein (CRY) stabilizer; blocks proteasome-mediated degradation of CRY1 and CRY2. Lengthens circadian period in mouse NIH-3T3 ...
KL001 is a cryptochrome protein stabilizer. It inhibits ubiquitin-induced degradation of cryptochrome 1 (CRY1) in HEK293T cells overexpressing CRY1 when ...
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The Cryptocrome Activator, KL001 modulates the biological activity of Cryptocrome. This small molecule/inhibitor is primarily used for Biochemicals ...
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KL001 is a stabilizer of cryptochrome (CRY). KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KEYWORDS ...
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KL-001 (CAS 309928-48-1) is a Cryptochrome (CRY) activator that prevents its degradation resulting in lengthening of the circadian period.
Sep 26, 2022 · SHP656 is an orally available KL001 derivative and has shown efficacy in blood glucose control and inhibition of glioblastoma stem cell (GSC) ...
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KL001 is a stabilizer that specifically interacts with cryptochrome (CRY). KL001 prevents ubiquitin-dependent degradation of CRY, resulting in lengthening ...